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What is phentermine?

Phentermine is a stimulant similar to an amphetamine. It acts as an appetite suppressant by affecting the central nervous system.

Phentermine is used together with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes.

Phentermine may also be used for purposes not listed in this medication guide.

Important information

Do not use phentermine if you are pregnant or breast-feeding a baby.

You should not take phentermine if you have a history of heart disease (coronary artery disease, heart rhythm problems, congestive heart failure, stroke), severe or uncontrolled high blood pressure, overactive thyroid, glaucoma, a history of pulmonary hypertension, if you are in an agitated state, or if you have a history of drug or alcohol abuse.

Do not use phentermine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Phentermine dosing information

Usual Adult Dose for Weight Loss:

15 to 37.5 mg orally once a day before breakfast or 1 to 2 hours after breakfast.

Usual Pediatric Dose for Weight Loss:

17 years or older:

15 to 37.5 mg orally once a day before breakfast or 1 to 2 hours after breakfast.